Ontology highlight
ABSTRACT:
SUBMITTER: Piasecka D
PROVIDER: S-EPMC6542018 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Piasecka Dominika D Braun Marcin M Kitowska Kamila K Mieczkowski Kamil K Kordek Radzislaw R Sadej Rafal R Romanska Hanna H
Journal of experimental & clinical cancer research : CR 20190529 1
Stromal stimuli mediated by growth factor receptors, leading to ligand-independent activation of steroid hormone receptors, have long been implicated in development of breast cancer resistance to endocrine therapy. Mutations in fibroblast growth factor receptor (FGFR) genes have been associated with a higher incidence and progression of breast cancer. Increasing evidence suggests that FGFR-mediated interaction between luminal invasive ductal breast carcinoma (IDC) and its microenvironment contri ...[more]