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Chaetomium atrobrunneum causing human eumycetoma: The first report.

ABSTRACT: In this communication, a case of black grain eumycetoma produced by the fungus C. atrobrunneum is reported. The patient was initially misdiagnosed with M. mycetomatis eumycetoma based on the grains' morphological and cytological features. However, further aerobic culture of the black grains generated a melanised fungus identified as C. atrobrunneum by conventional morphological methods and by internal transcribed spacer 2 (ITS2) ribosomal RNA gene sequencing. This is the first-ever report of C. atrobrunneum as a eumycetoma-causative organism of black grain eumycetoma. It is essential that the causative organism is identified to the species level, as this is important for proper patient management and to predict treatment outcome and prognosis.

SUBMITTER: Mhmoud NA

PROVIDER: S-EPMC6542518 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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Chaetomium atrobrunneum causing human eumycetoma: The first report.

Mhmoud Najwa A NA Santona Antonella A Fiamma Maura M Siddig Emmanuel Edwar EE Deligios Massimo M Bakhiet Sahar Mubarak SM Bakhiet Sahar Mubarak SM Rubino Salvatore S Fahal Ahmed Hassan AH

PLoS neglected tropical diseases 20190530 5

In this communication, a case of black grain eumycetoma produced by the fungus C. atrobrunneum is reported. The patient was initially misdiagnosed with M. mycetomatis eumycetoma based on the grains' morphological and cytological features. However, further aerobic culture of the black grains generated a melanised fungus identified as C. atrobrunneum by conventional morphological methods and by internal transcribed spacer 2 (ITS2) ribosomal RNA gene sequencing. This is the first-ever report of C. ...[more]

PMID: 31145740

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