Ontology highlight
ABSTRACT:
SUBMITTER: Pedro L
PROVIDER: S-EPMC6542677 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Pedro Luisa L Harmer Quentin Q Mayes Eric E Shields Jacqueline D JD
Small (Weinheim an der Bergstrasse, Germany) 20190415 20
Interstitially administered iron oxide particles are currently used for interoperative localization of sentinel lymph nodes (LNs) in cancer staging. Several studies have described concerns regarding the cellular accumulation of iron oxide nanoparticles relating them to phenotype and function deregulation of macrophages, impairing their ability to mount an appropriate immune response once an insult is present. This study aims to address what phenotypic and functional changes occur during lymphati ...[more]