Ontology highlight
ABSTRACT:
SUBMITTER: Lin BM
PROVIDER: S-EPMC6544117 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Lin Bridget M BM Nadkarni Girish N GN Tao Ran R Graff Mariaelisa M Fornage Myriam M Buyske Steven S Matise Tara C TC Highland Heather M HM Wilkens Lynne R LR Carlson Christopher S CS Park S Lani SL Setiawan V Wendy VW Ambite Jose Luis JL Heiss Gerardo G Boerwinkle Eric E Lin Dan-Yu DY Morris Andrew P AP Loos Ruth J F RJF Kooperberg Charles C North Kari E KE Wassel Christina L CL Franceschini Nora N
Frontiers in genetics 20190524
<h4>Background</h4>Chronic kidney disease (CKD) is common and disproportionally burdens United States ethnic minorities. Its genetic determinants may differ by disease severity and clinical stages. To uncover genetic factors associated CKD severity among high-risk ethnic groups, we performed genome-wide association studies (GWAS) in diverse populations within the Population Architecture using Genomics and Epidemiology (PAGE) study.<h4>Methods</h4>We assembled multi-ethnic genome-wide imputed dat ...[more]