Ontology highlight
ABSTRACT:
SUBMITTER: Wenzel M
PROVIDER: S-EPMC6544156 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Wenzel Michael M Han Shuting S Smith Elliot H EH Hoel Erik E Greger Bradley B House Paul A PA Yuste Rafael R
Cell systems 20190501 5
Medically induced loss of consciousness (mLOC) during anesthesia is associated with a macroscale breakdown of brain connectivity, yet the neural microcircuit correlates of mLOC remain unknown. To explore this, we applied different analytical approaches (t-SNE/watershed segmentation, affinity propagation clustering, PCA, and LZW complexity) to two-photon calcium imaging of neocortical and hippocampal microcircuit activity and local field potential (LFP) measurements across different anesthetic de ...[more]