Patient and general population values for luminal and perianal fistulising Crohn's disease health states.

ABSTRACT:

Background

In patients with Crohn's disease (CD), luminal disease activity paralleled by perianal fistulas may seriously impair health-related quality of life (HRQoL). Health utility values are not available from patients with CD that reflect the health loss associated with both luminal and perianal CD.

Objective

To generate utilities for luminal and concomitant perianal fistulising CD health states directly from patients and from members of the general public.

Methods

A cross-sectional survey was undertaken enrolling CD patients and a convenience sample of members of the general population. Respondents were asked to evaluate four common CD heath states [severe luminal disease (sCD), mild luminal disease (mCD), severe luminal disease with active perianal fistulas (sPF

SUBMITTER: Rencz F 

PROVIDER: S-EPMC6544586 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature