Total adiponectin in overweight and obese subjects and its response to visceral fat loss.

ABSTRACT: BACKGROUND:Visceral obesity and related diabetes is reaching epidemic proportions in the United Arab Emirates (UAE). Adiponectin is a hormone that is secreted by adipose tissue and may play an important role in obesity-related morbidity. The aim of this study was to investigate total adiponectin levels in overweight and obese UAE subjects visiting health care facilities for weight management. METHODS:All overweight and obese subjects visiting community health centers were invited to take part in the study. Two hundred and six participants received individualized structured dietary education for weight management. Demographic data, anthropometric measurements and fasting venous blood samples were taken for measurements of total adiponectin and markers of inflammation and nutritional status at baseline and follow up. Multivariate analysis was performed to determine the independent effects of prognostic factors on serum adiponectin levels. RESULTS:A total of 193 (93%) females with a mean age (±SD) 36?±?11?years were included in the analysis. During a follow up period of 427?±?223?days, participants received 13?±?5 structured dietary education sessions. We observed decreased levels of total adiponectin with increasing quartiles of both waist circumference (WC) and body mass index (BMI). Male gender and history of both gestational and type 2 diabetes were associated with significantly lower total adiponectin levels (p?

SUBMITTER: Gariballa S 

PROVIDER: S-EPMC6545728 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature