TissueEnrich: Tissue-specific gene enrichment analysis.

ABSTRACT:

Summary

RNA-Seq data analysis results in lists of genes that may have a similar function, based on differential gene expression analysis or co-expression network analysis. While tools have been developed to identify biological processes that are enriched in the genes sets, there remains a need for tools that identify enrichment of tissue-specific genes. Therefore, we developed TissueEnrich, a tool that calculates tissue-specific gene enrichment in an input gene set. We demonstrated that TissueEnrich can assign tissue identities to single cell clusters and differentiated embryonic stem cells.

Availability and implementation

The TissueEnrich web application is freely available at http://tissueenrich.gdcb.iastate.edu/. The R package is available through Bioconductor at https://

SUBMITTER: Jain A 

PROVIDER: S-EPMC6546155 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature