Ontology highlight
ABSTRACT:
SUBMITTER: Common J
PROVIDER: S-EPMC6546380 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
RNA biology 20190217 4
Population bottlenecks often cause strong reductions in genetic diversity and alter population structure. In the context of host-parasite interactions, bottlenecks could in theory benefit either the host or the pathogen. We predicted that bottlenecking of bacterial populations that evolve CRISPR immunity against bacteriophages (phage) would benefit the pathogen, because CRISPR spacer diversity can rapidly drive phages extinct. To test this, we bottlenecked populations of bacteria and phage, trac ...[more]