Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze.

ABSTRACT:

Importance

Rhinovirus infection in early life, particularly with allergic sensitization, is associated with higher risks of developing recurrent wheeze and asthma. While emerging evidence links different rhinovirus species (eg, rhinovirus C) to a higher severity of infection and asthma exacerbation, to our knowledge, little is known about longitudinal associations of rhinovirus C infection during infancy with subsequent morbidities.

Objective

To examine the association of different viruses (respiratory syncytial virus [RSV], rhinovirus species) in bronchiolitis with risks of developing recurrent wheeze.

Design, setting, and participants

This multicenter prospective cohort study of infants younger than 1 year who were hospitalized for bronchiolitis was conducted at 17

SUBMITTER: Hasegawa K 

PROVIDER: S-EPMC6547078 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature