Ontology highlight
ABSTRACT:
SUBMITTER: Glasgow MA
PROVIDER: S-EPMC6547356 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Glasgow Michelle A MA Argenta Peter P Abrahante Juan E JE Shetty Mihir M Talukdar Shobhana S Croonquist Paula A PA Khalifa Mahmoud A MA Starr Timothy K TK
International journal of molecular sciences 20190430 9
The majority of patients with high-grade serous ovarian cancer (HGSOC) initially respond to chemotherapy; however, most will develop chemotherapy resistance. Gene signatures may change with the development of chemotherapy resistance in this population, which is important as it may lead to tailored therapies. The objective of this study was to compare tumor gene expression profiles in patients before and after treatment with neoadjuvant chemotherapy (NACT). Tumor samples were collected from six p ...[more]