Dataset Information

Prefrontal-posterior coupling mediates transitions between emotional states and influences executive functioning.

ABSTRACT: Emotions often result from fluctuating experiences with self-regulation unfolding over time. However, most research has been focused on neural responses to static, affective stimuli. We studied emotion transitions, which correspond to dynamic conditions of varying affective valence or intensities. Functional coupling of prefrontal and posterior cortex (EEG coherence) was recorded during exposure to stable versus changing emotion-eliciting images (static vs. dynamic conditions). Prefrontal-posterior coupling was decreased in the dynamic conditions compared to the static conditions. A decrease in prefrontal-posterior coupling implies less control of the prefrontal cortex over perceptual information, which may allow the brain to become more affected by emotional fluctuations. We also assessed the aftereffect of EEG coherence on executive functioning, utilizing the flanker task. Among individuals reporting higher chronic stress, executive functioning decreased after dynamic conditions. This decrease in executive functioning was mediated by the decrease in prefrontal-posterior coupling in the dynamic conditions. These findings suggest that the strength of prefrontal-posterior coupling is not only related to emotional transitions but also to executive functioning. The deterioration of executive functioning after dynamic emotional processing may reflect the additional cognitive effort required to process dynamic shifts in affective stimuli, and this relationship is exacerbated by chronic stress.

SUBMITTER: Hao Y

PROVIDER: S-EPMC6547671 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Prefrontal-posterior coupling mediates transitions between emotional states and influences executive functioning.

Hao Yu Y Yao Lin L Smith Derek M DM Sorel Edward E Anderson Adam K AK Schumacher Eric H EH Evans Gary W GW

Scientific reports 20190604 1

Emotions often result from fluctuating experiences with self-regulation unfolding over time. However, most research has been focused on neural responses to static, affective stimuli. We studied emotion transitions, which correspond to dynamic conditions of varying affective valence or intensities. Functional coupling of prefrontal and posterior cortex (EEG coherence) was recorded during exposure to stable versus changing emotion-eliciting images (static vs. dynamic conditions). Prefrontal-poster ...[more]

PMID: 31164677

Similar Datasets

Project description:IntroductionIntermittent theta-burst stimulation (iTBS) is a non-invasive brain stimulation paradigm that has demonstrated promising therapeutic benefits for a variety of neuropsychiatric disorders. It has recently garnered widespread favor among researchers and clinicians, owing to its comparable potentiation effects as conventional high-frequency repetitive transcranial magnetic stimulation (rTMS), but administered in a much shorter time frame. However, there is still a lack of agreement over the optimal stimulation intensity, particularly when targeting the prefrontal regions. The objective of this study was to systematically investigate the influence of different stimulation intensities of iTBS, applied over the left dorsolateral prefrontal cortex (DLPFC), on brain activity and executive function in healthy adults.MethodsTwenty young healthy adults were enrolled in this randomized cross-over experiment. All participants received a single session iTBS over the left DLPFC at intensities of 50, 70, or 100% of their individual resting motor threshold (RMT), each on separate visits. Functional near-infrared spectroscopy (fNIRS) was used to measure changes of hemoglobin concentrations in prefrontal areas during the verbal fluency task (VFT) before and after stimulation.ResultsAfter stimulation, iTBS to the left DLPFC with 70% RMT maintained the concentration change of oxyhemoglobin (HbO) in the target area during the VFT. In contrast, 50% [t (17) = 2.203, P = 0.042, d = 0.523] and 100% iTBS [t (17) = 2.947, P = 0.009, d = 0.547] significantly decreased change of HbO concentration, indicating an inverse U-shape relationship between stimulation intensity and prefrontal hemodynamic response in healthy young adults. Notably, improved VFT performance was only observed after 70% RMT stimulation [t (17) = 2.511, P = 0.022, d = 0.592]. Moreover, a significant positive correlation was observed between task performance and the difference in HbO concentration change in the targeted area after 70% RMT stimulation (r = 0.496, P = 0.036) but not after 50 or 100% RMT stimulation.ConclusionThe linear relationship between stimulation intensity and behavioral outcomes reported in previous conventional rTMS studies may not be translated to iTBS. Instead, iTBS at 70% RMT may be more efficacious than 100% RMT.

Dataset Information

Prefrontal-posterior coupling mediates transitions between emotional states and influences executive functioning.

Publications

Prefrontal-posterior coupling mediates transitions between emotional states and influences executive functioning.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets