Ontology highlight
ABSTRACT:
SUBMITTER: Hart SFM
PROVIDER: S-EPMC6548503 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Hart Samuel Frederick Mock SFM Pineda Jose Mario Bello JMB Chen Chi-Chun CC Green Robin R Shou Wenying W
eLife 20190604
Mutualisms can be promoted by pleiotropic win-win mutations which directly benefit self (self-serving) and partner (partner-serving). Intuitively, partner-serving phenotype could be quantified as an individual's benefit supply rate to partners. Here, we demonstrate the inadequacy of this thinking, and propose an alternative. Specifically, we evolved well-mixed mutualistic communities where two engineered yeast strains exchanged essential metabolites lysine and hypoxanthine. Among cells that cons ...[more]