Ontology highlight
ABSTRACT:
SUBMITTER: Kharazmi-Khorassani S
PROVIDER: S-EPMC6549319 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Kharazmi-Khorassani Sara S Kharazmi-Khorassani Jasmin J Rastegar-Moghadam Azam A Samadi Sara S Ghazizadeh Hamideh H Tayefi Maryam M Ferns Gordon A GA Ghayour-Mobarhan Majid M Avan Amir A Esmaily Habibollah H
BMC medical genetics 20190604 1
<h4>Background</h4>Metabolic syndrome (MetS) is characterized by a clustering of cardiovascular risk factors that include: abdominal obesity, dyslipidemia, hypertension and glucose intolerance. Angiopoietin-like protein 4 (ANGPTL4) is a circulating peptide that is an inhibitor of lipoprotein lipase, a key enzyme in lipid metabolism. The objective of this study was to investigate the association of ANGPTL4 gene variants (E40K) with fasting serum triglyceride levels and with cardiovascular risk fa ...[more]