Ontology highlight
ABSTRACT:
SUBMITTER: Wu T
PROVIDER: S-EPMC6551028 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Wu Ting T Wang Meng M Wu Wenfang W Luo Qianxuan Q Jiang Liping L Tao Huai H Deng Meichun M
The journal of venomous animals and toxins including tropical diseases 20190603
Spider venoms are known to contain proteins and polypeptides that perform various functions including antimicrobial, neurotoxic, analgesic, cytotoxic, necrotic, and hemagglutinic activities. Currently, several classes of natural molecules from spider venoms are potential sources of chemotherapeutics against tumor cells. Some of the spider peptide toxins produce lethal effects on tumor cells by regulating the cell cycle, activating caspase pathway or inactivating mitochondria. Some of them also t ...[more]