Development of 68Ga-labelled ultrasound microbubbles for whole-body PET imaging.
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ABSTRACT:
SUBMITTER: Hernandez-Gil J
PROVIDER: S-EPMC6552490 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Publications
Development of <sup>68</sup>Ga-labelled ultrasound microbubbles for whole-body PET imaging.
Hernández-Gil Javier J Braga Marta M Harriss Bethany I BI Carroll Laurence S LS Leow Chee Hau CH Tang Meng-Xing MX Aboagye Eric O EO Long Nicholas J NJ
Chemical science 20190501 21
Microbubble (MB) contrast agents have revolutionalised the way ultrasound (US) imaging can be used clinically and pre-clinically. Contrast-enhanced US offers improvements in soft-tissue contrast, as well as the ability to visualise disease processes at the molecular level. However, its inability to provide <i>in vivo</i> whole-body imaging can hamper the development of new MB formulations. Herein, we describe a fast and efficient method for achieving <sup>68</sup>Ga-labelling of MBs after a dire ...[more]
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