Ontology highlight
ABSTRACT:
SUBMITTER: Hecht M
PROVIDER: S-EPMC6553528 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Hecht Matthias M Rösler Reinhild R Wiese Sebastian S Johnsson Nils N Gronemeyer Thomas T
G3 (Bethesda, Md.) 20190605 6
Septins regulate the organization of the actin cytoskeleton, vesicle transport and fusion, chromosome alignment and segregation, and cytokinesis in mammalian cells. SEPT9 is part of the core septin hetero-octamer in human cells which is composed of SEPT2, SEPT6, SEPT7, and SEPT9. SEPT9 has been linked to a variety of intracellular functions as well as to diseases and diverse types of cancer. A targeted high-throughput approach to systematically identify the interaction partners of SEPT9 has not ...[more]