Ontology highlight
ABSTRACT:
SUBMITTER: Carlin DE
PROVIDER: S-EPMC6554232 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Carlin Daniel E DE Fong Samson H SH Qin Yue Y Jia Tongqiu T Huang Justin K JK Bao Bokan B Zhang Chao C Ideker Trey T
iScience 20190524
We present an accessible, fast, and customizable network propagation system for pathway boosting and interpretation of genome-wide association studies. This system-NAGA (Network Assisted Genomic Association)-taps the NDEx biological network resource to gain access to thousands of protein networks and select those most relevant and performative for a specific association study. The method works efficiently, completing genome-wide analysis in under 5 minutes on a modern laptop computer. We show th ...[more]