Age-related hearing loss accelerates cerebrospinal fluid tau levels and brain atrophy: a longitudinal study.
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ABSTRACT:
SUBMITTER: Xu W
PROVIDER: S-EPMC6555452 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Publications
Age-related hearing loss accelerates cerebrospinal fluid tau levels and brain atrophy: a longitudinal study.
Xu Wei W Zhang Can C Li Jie-Qiong JQ Tan Chen-Chen CC Cao Xi-Peng XP Tan Lan L Yu Jin-Tai JT
Aging 20190501 10
Age-related hearing loss (ARHL) has been considered as a promising modifiable risk factor for cognitive impairment and dementia. Nonetheless, it is still unclear whether age-related hearing loss associates with neurodegenerative biomarkers of Alzheimer's disease (AD). Participants with ARHL were selected from the established Alzheimer's Disease Neuroimaging Initiative (ADNI) database. In multivariable models, the cross-sectional and longitudinal associations of ARHL with CSF β-amyloid (Aβ) and t ...[more]
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