Ontology highlight
ABSTRACT:
SUBMITTER: He M
PROVIDER: S-EPMC6555468 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
He Mengying M Wang Jin J Yin Zhongwei Z Zhao Yanru Y Hou Huiying H Fan Jiahui J Li Huaping H Wen Zheng Z Tang Jiarong J Wang Yan Y Wang Dao Wen DW Chen Chen C
Aging 20190501 10
Multiple studies indicate that microRNAs (miRNAs) are involved in diabetes. However, the roles of miRNA in the target organ damages in diabetes remain unclear. This study investigated the functions of miR-320a in diabetic nephropathy (DN). In this study, db/db mice were used to observe the changes in podocytes and their function in vivo, as well as in cultured mouse podocyte cells (MPC5) exposed to high glucose in vitro. To further explore the role of miR-320a in DN, recombinant adeno-associated ...[more]