Ontology highlight
ABSTRACT:
SUBMITTER: Perumal J
PROVIDER: S-EPMC6555913 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Perumal Jai J Fox Robert J RJ Balabanov Roumen R Balcer Laura J LJ Galetta Steven S Makh Shavy S Santra Sourav S Hotermans Christophe C Lee Lily L
BMC neurology 20190608 1
<h4>Background</h4>STRIVE is a multicenter, observational, open-label, single-arm study of natalizumab in anti-JC virus (JCV) seronegative patients with early relapsing-remitting multiple sclerosis (RRMS). The objective of this prespecified 2-year interim analysis was to determine the effectiveness of natalizumab in establishing and maintaining no evidence of disease activity (NEDA) in early RRMS.<h4>Methods</h4>Patients aged 18-65 years had an RRMS diagnosis < 3 years prior to screening, an Exp ...[more]