Ontology highlight
ABSTRACT:
SUBMITTER: Gu H
PROVIDER: S-EPMC6556634 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Gu Huijie H Wu Liang L Chen Haihong H Huang Zhongyue Z Xu Jun J Zhou Kaifeng K Zhang Yiming Y Chen Jiong J Xia Jiangni J Yin Xiaofan X
American journal of translational research 20190515 5
This study aimed to identify specific microRNAs (miRNAs) related to postmenopausal osteoporosis (OP) in human. A total of 67 conserved miRNAs, including 50 miRNAs significantly up-regulated and 17 miRNAs significantly downregulated, showed differential expression between OP group and control group. 180 hairpin structures were predicted and 199 potential novel miRNA candidates with 18 to 25 nt in length, which will greatly enrich the human miRBase. 4 miRNAs (miR-518b, miR-582-3p, miR-148a-3p and ...[more]