Ontology highlight
ABSTRACT:
SUBMITTER: Tsoukalas D
PROVIDER: S-EPMC6559326 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Tsoukalas Dimitris D Fragkiadaki Persefoni P Docea Anca Oana AO Alegakis Athanasios K AK Sarandi Evangelia E Vakonaki Elena E Salataj Eralda E Kouvidi Elisavet E Nikitovic Dragana D Kovatsi Leda L Spandidos Demetrios A DA Tsatsakis Aristidis A Calina Daniela D
International journal of molecular medicine 20190510 1
Telomeres are nucleotide tandem repeats located at the tip of eukaryotic chromosomes that maintain genomic integrity. The gradual shortening of telomeres leads to cellular senescence and apoptosis, a key mechanism of aging and age‑related chronic diseases. Epigenetic factors, such as nutrition, exercise and tobacco can affect the rate at which telomeres shorten and can modify the risk of developing chronic diseases. In this study, we evaluated the effects of a combination of nutraceutical supple ...[more]