Dataset Information

Trends in the incidence of testing for vitamin D deficiency in primary care in the UK: a retrospective analysis of The Health Improvement Network (THIN), 2005-2015.

ABSTRACT:

Objective

To investigate trends in the incidence of testing for vitamin D deficiency and the prevalence of patients with circulating concentrations of 25-hydroxyvitamin D (25(OH)D) indicative of deficiency (<30?nmol/L) between 2005 and 2015.

Design

Longitudinal analysis of electronic health records in The Health Improvement Network primary care database.

Setting

UK primary care.

Intervention

None.

Participants

The analysis included 6 416 709 participants aged 18 years and older.

Primary outcomes

Incidence of having a blood test for vitamin D deficiency between 2005 and 2015, the prevalence with blood 25(OH)D <30?nmol/L and the effects of age, ethnicity and socioeconomic status on these measures were assessed.

Results

After a mean follow-up time of 5.4 (SD 3.7) years, there were 210?502 patients tested for vitamin D deficiency. The incidence of vitamin D testing rose from 0.29 per 1000 person-years at risk (PYAR) (95%?CI 0.27 to 0.31) in 2005 to 16.1 per 1000 PYAR (95%?CI 15.9 to 16.2) in 2015. Being female, older, non-white ethnicity and more economically deprived were all strongly associated with being tested. One-third (n=69?515) had 25(OH)D <30?nmol/L, but the per cent deficient among ethnic minority groups ranged from 43% among mixed ethnicity to 66% in Asians. Being male, younger and more economically deprived were also all associated with vitamin D deficiency (p<0.001).

Conclusions

Testing for vitamin D deficiency increased over the past decade among adults in the UK. One-third of UK adults who had a vitamin D test performed in primary care were vitamin D deficient, and deficiency was much higher among ethnic minority patients. Future research should focus on strategies to ensure population intake of vitamin D, particularly in at-risk groups, meets recommendations to reduce the risk of deficiency and need for testing.

SUBMITTER: Crowe FL

PROVIDER: S-EPMC6561453 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Trends in the incidence of testing for vitamin D deficiency in primary care in the UK: a retrospective analysis of The Health Improvement Network (THIN), 2005-2015.

Crowe Francesca L FL Jolly Kate K MacArthur Christine C Manaseki-Holland Semira S Gittoes Neil N Hewison Martin M Scragg Robert R Nirantharakumar Krishnarajah K

BMJ open 20190604 6

<h4>Objective</h4>To investigate trends in the incidence of testing for vitamin D deficiency and the prevalence of patients with circulating concentrations of 25-hydroxyvitamin D (25(OH)D) indicative of deficiency (<30 nmol/L) between 2005 and 2015.<h4>Design</h4>Longitudinal analysis of electronic health records in The Health Improvement Network primary care database.<h4>Setting</h4>UK primary care.<h4>Intervention</h4>None.<h4>Participants</h4>The analysis included 6 416 709 participants aged ...[more]

PMID: 31167871

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Dataset Information

Trends in the incidence of testing for vitamin D deficiency in primary care in the UK: a retrospective analysis of The Health Improvement Network (THIN), 2005-2015.

Objective

Design

Setting

Intervention

Participants

Primary outcomes

Results

Conclusions

Publications

Trends in the incidence of testing for vitamin D deficiency in primary care in the UK: a retrospective analysis of The Health Improvement Network (THIN), 2005-2015.

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