Ontology highlight
ABSTRACT:
SUBMITTER: Mazade R
PROVIDER: S-EPMC6561493 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Mazade Reece R Jin Jianzhong J Pons Carmen C Alonso Jose-Manuel JM
Cell reports 20190601 10
Visual information is processed in the cortex by ON and OFF pathways that respond to light and dark stimuli. Responses to darks are stronger, faster, and driven by a larger number of cortical neurons than responses to lights. Here, we demonstrate that these light-dark cortical asymmetries reflect a functional specialization of ON and OFF pathways for different stimulus properties. We show that large long-lasting stimuli drive stronger cortical responses when they are light, whereas small fast st ...[more]