Ontology highlight
ABSTRACT:
SUBMITTER: Kim JL
PROVIDER: S-EPMC6562873 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Kim Jung Lim JL Kim Bo Ram BR Kim Dae Yeong DY Jeong Yoon A YA Jeong Soyeon S Na Yoo Jin YJ Park Seong Hye SH Yun Hye Kyeong HK Jo Min Jee MJ Kim Bu Gyeom BG Kim Han Do HD Kim Dae Hyun DH Oh Sang Cheul SC Lee Sun Il SI Lee Dae-Hee DH
Cancers 20190509 5
Cannabidiol, a major non-psychotomimetic compound derived from <i>Cannabis sativa</i>, is a potential therapeutic agent for a variety of diseases such as inflammatory diseases, chronic neurodegenerative diseases, and cancers. Here, we found that the combination of cannabidiol and TNF-related apoptosis-inducing ligand (TRAIL) produces synergistic antitumor effects in vitro. However, this synergistic effect was not observed in normal colonic cells. The levels of ER stress-related proteins, includi ...[more]