Ontology highlight
ABSTRACT:
SUBMITTER: Thiry D
PROVIDER: S-EPMC6563190 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Thiry Damien D Passet Virginie V Danis-Wlodarczyk Katarzyna K Lood Cédric C Wagemans Jeroen J De Sordi Luisa L van Noort Vera V Dufour Nicolas N Debarbieux Laurent L Mainil Jacques G JG Brisse Sylvain S Lavigne Rob R
Viruses 20190503 5
<i>Klebsiella pneumoniae</i> is a bacterial pathogen of high public health importance. Its polysaccharide capsule is highly variable but only a few capsular types are associated with emerging pathogenic sublineages. The aim of this work is to isolate and characterize new lytic bacteriophages and assess their potential to control infections by the ST23 and ST258 <i>K. pneumoniae</i> sublineages using a <i>Galleria mellonella</i> larvae model. Three selected bacteriophages, targeting lineages ST25 ...[more]