Ontology highlight
ABSTRACT:
SUBMITTER: Tieves F
PROVIDER: S-EPMC6563469 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20190430 23
An increasing number of biocatalytic oxidation reactions rely on H<sub>2</sub> O<sub>2</sub> as a clean oxidant. The poor robustness of most enzymes towards H<sub>2</sub> O<sub>2</sub> , however, necessitates more efficient systems for in situ H<sub>2</sub> O<sub>2</sub> generation. In analogy to the well-known formate dehydrogenase to promote NADH-dependent reactions, we here propose employing formate oxidase (FOx) to promote H<sub>2</sub> O<sub>2</sub> -dependent enzymatic oxidation reactions. ...[more]