Ontology highlight
ABSTRACT:
SUBMITTER: Reynolds JA
PROVIDER: S-EPMC6567906 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Reynolds John A JA Briggs Tracy A TA Rice Gillian I GI Darmalinggam Sathya S Bondet Vincent V Bruce Ellen E Khan Mumtaz M Haque Sahena S Chinoy Hector H Herrick Ariane L AL McCarthy Eoghan M EM Zeef Leo L Hayes Andrew A Duffy Darragh D Parker Ben B Bruce Ian N IN
Arthritis research & therapy 20190614 1
<h4>Objectives</h4>To investigate the relationships between interferon alpha (IFNα) and the clinical and serological phenotype of patients with systemic autoimmune rheumatic disease (SARDs) in order to determine whether a distinct subpopulation of patients can be identified.<h4>Methods</h4>We recruited patients with at least 1 SARD clinical feature and at least 1 SARD-related autoantibody from two NHS Trusts in Greater Manchester. A 6-gene interferon-stimulated gene (ISG) score was calculated in ...[more]