Conjugative Transfer of the pVA1-Type Plasmid Carrying the pirAB ^vp Genes Results in the Formation of New AHPND-Causing Vibrio.

ABSTRACT: Acute hepatopancreatic necrosis disease (AHPND) has caused sharp declines in aquaculture industries of whiteleg shrimp Penaeus vannamei in Asia and the Americas since 2010. Vibrio parahaemolyticus, V. campbellii, V. owensii, and V. punensis have been proved to cause AHPND. However, the mechanisms underlying the burgeoning number of Vibrio species that cause AHPND is not known. All of AHPND-causing Vibrio bacteria (V _AHPND) harbor a highly homologous plasmid (designated as pVA1-type) carrying pirAB ^vp toxin genes. In this study, we demonstrate conclusively that the pVA1-type plasmid can be transferred from V _AHPND to non-pathogenic bacteria. We constructed a pVPGX1-Cm ^r p

SUBMITTER: Dong X 

PROVIDER: S-EPMC6568040 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature