Ontology highlight
ABSTRACT:
SUBMITTER: Sarmiento-Salinas FL
PROVIDER: S-EPMC6568240 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Sarmiento-Salinas Fabiola Lilí FL Delgado-Magallón Alam A Montes-Alvarado José Benito JB Ramírez-Ramírez Dalia D Flores-Alonso Juan Carlos JC Cortés-Hernández Paulina P Reyes-Leyva Julio J Herrera-Camacho Irma I Anaya-Ruiz Maricruz M Pelayo Rosana R Millán-Pérez-Peña Lourdes L Maycotte Paola P
Frontiers in oncology 20190607
Due to their crucial role in cell metabolism and homeostasis, alterations in mitochondrial biology and function have been related to the progression of diverse diseases including cancer. One of the consequences associated to mitochondrial dysfunction is the production of reactive oxygen species (ROS). ROS are known to have a controversial role during cancer initiation and progression and although several studies have tried to manipulate intracellular ROS levels using antioxidants or pro-oxidatio ...[more]