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ABSTRACT: Objectives
Beneficial effects of overweight and obesity on mortality after acute myocardial infarction (AMI) have been described as "Body Mass Index (BMI) paradox". However, the effects of BMI is still on debate. We analyzed the association between BMI and 1-year clinical outcomes after AMI.Methods
Among 13,104 AMI patients registered in Korea Acute Myocardial Infarction Registry-National Institute of Health (KAMIR-NIH) between November 2011 and December 2015, 10,568 patients who eligible for this study were classified into 3 groups according to BMI (Group 1; < 22 kg/m2, 22 ? Group 2 < 26 kg/m2, Group 3; ? 26 kg/m2). The primary end point was all cause death at 1 year.Results
Over the median follow-up of 12 months, the event of primary end point occurred more frequently in the Group 1 patients than in the Group 3 patients (primary endpoint: adjusted hazard ratio [aHR], 1.537; 95% confidence interval [CI] 1.177 to 2.007, p = 0.002). Especially, cardiac death played a major role in this effect (aHR, 1.548; 95% confidence interval [CI] 1.128 to 2.124, p = 0.007).Conclusions
Higher BMI appeared to be good prognostic factor on 1-year all cause death after AMI. This result suggests that higher BMI or obesity might confer a protective advantage over the life-quality after AMI.
SUBMITTER: Kim DW
PROVIDER: S-EPMC6570024 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Kim Dae-Won DW Her Sung-Ho SH Park Ha Wook HW Park Mahn-Won MW Chang Kiyuk K Chung Wook Sung WS Seung Ki Bae KB Ahn Tae Hoon TH Jeong Myung Ho MH Rha Seung-Woon SW Kim Hyo-Soo HS Gwon Hyeon Cheol HC Seong In Whan IW Hwang Kyung Kuk KK Chae Shung Chull SC Kim Kwon-Bae KB Kim Young Jo YJ Cha Kwang Soo KS Oh Seok Kyu SK Chae Jei Keon JK
PloS one 20190614 6
<h4>Objectives</h4>Beneficial effects of overweight and obesity on mortality after acute myocardial infarction (AMI) have been described as "Body Mass Index (BMI) paradox". However, the effects of BMI is still on debate. We analyzed the association between BMI and 1-year clinical outcomes after AMI.<h4>Methods</h4>Among 13,104 AMI patients registered in Korea Acute Myocardial Infarction Registry-National Institute of Health (KAMIR-NIH) between November 2011 and December 2015, 10,568 patients who ...[more]