Ontology highlight
ABSTRACT:
SUBMITTER: Peck SA
PROVIDER: S-EPMC6570551 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Peck Sarah A SA Hughes Katlyn D KD Victorino Jose F JF Mosley Amber L AL
Wiley interdisciplinary reviews. RNA 20190307 4
Processing and maturation of precursor RNA species is coupled to RNA polymerase II transcription. Co-transcriptional RNA processing helps to ensure efficient and proper capping, splicing, and 3' end processing of different RNA species to help ensure quality control of the transcriptome. Many improperly processed transcripts are not exported from the nucleus, are restricted to the site of transcription, and are in some cases degraded, which helps to limit any possibility of aberrant RNA causing h ...[more]