Chelidonic Acid and Its Derivatives from Saussurea Controversa: Isolation, Structural Elucidation and Influence on the Osteogenic Differentiation of Multipotent Mesenchymal Stromal Cells In Vitro.
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ABSTRACT:
SUBMITTER: Avdeeva E
PROVIDER: S-EPMC6572306 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
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Chelidonic Acid and Its Derivatives from <i>Saussurea Controversa</i>: Isolation, Structural Elucidation and Influence on the Osteogenic Differentiation of Multipotent Mesenchymal Stromal Cells In Vitro.
Avdeeva Elena E Shults Elvira E Rybalova Tatyana T Reshetov Yaroslav Y Porokhova Ekaterina E Sukhodolo Irina I Litvinova Larisa L Shupletsova Valeria V Khaziakhmatova Olga O Khlusov Igor I Guryev Artem A Belousov Mikhail M
Biomolecules 20190516 5
4-oxo-4<i>H</i>-pyran-2.6-dicarboxylic acid (chelidonic acid, ChA) in the native state and in the complex with calcium [Ca(ChA)(H<sub>2</sub>O)<sub>3</sub>], named saucalchelin (CaChA), was isolated from the extract of <i>Saussurea controversa</i> leaves for the first time for the <i>Asteraceae</i> family. The structure of ChA was determined by NMR, MS and confirmed by X-ray analysis of its monomethyl ester, and CaChA was described by IR, ICP-MS, CHN analysis. The yield of ChA and CaChA was 45 m ...[more]
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