Ontology highlight
ABSTRACT:
SUBMITTER: Kopcial M
PROVIDER: S-EPMC6572376 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Kopcial Michal M Wojtczak Blazej A BA Kasprzyk Renata R Kowalska Joanna J Jemielity Jacek J
Molecules (Basel, Switzerland) 20190517 10
The mRNA 5' cap consists of N7-methylguanosine bound by a 5',5'-triphosphate bridge to the first nucleotide of the transcript. The cap interacts with various specific proteins and participates in all key mRNA-related processes, which may be of therapeutic relevance. There is a growing demand for new biophysical and biochemical methods to study cap-protein interactions and identify the factors which inhibit them. The development of such methods can be aided by the use of properly designed fluores ...[more]