Ontology highlight
ABSTRACT:
SUBMITTER: Lambert RC
PROVIDER: S-EPMC6573151 | biostudies-literature | 1997 Sep
REPOSITORIES: biostudies-literature
Lambert R C RC Maulet Y Y Mouton J J Beattie R R Volsen S S De Waard M M Feltz A A
The Journal of neuroscience : the official journal of the Society for Neuroscience 19970901 17
At the molecular level, our knowledge of the low voltage-activated Ca2+ channel (T-type) has made little progress. Using an antisense strategy, we investigated the possibility that the T-type channels have a structure similar to high voltage-activated Ca2+ channels. It is assumed that high voltage-activated channels are made of at least three components: a pore forming alpha1 subunit combined with a cytoplasmic modulatory beta subunit and a primarily extracellular alpha2delta subunit. We have ex ...[more]