Ontology highlight
ABSTRACT:
SUBMITTER: Werbel WA
PROVIDER: S-EPMC6579039 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Werbel William A WA Durand Christine M CM
Current HIV/AIDS reports 20190601 3
<h4>Purpose of review</h4>End-stage organ disease prevalence is increasing among HIV-infected (HIV+) individuals. Trial and registry data confirm that solid organ transplantation (SOT) is efficacious in this population. Optimizing access to transplant and decreasing complications represent active frontiers.<h4>Recent findings</h4>HIV+ recipients historically experienced 2-4-fold higher rejection. Integrase strand transferase inhibitors (INSTIs) minimize drug interactions and may reduce rejection ...[more]