Dataset Information

High Isotropic Resolution T2 Mapping of the Lumbosacral Plexus with T2-Prepared 3D Turbo Spin Echo.

ABSTRACT: PURPOSE:Isotropic high-resolution three-dimensional (3D) magnetic resonance neurography (MRN) is increasingly used to depict even small and highly oblique nerves of the lumbosacral plexus (LSP). The present study introduces a T2 mapping sequence (T2-prepared 3D turbo spin echo) that is B1-insensitive and enables quantitative assessment of LSP nerves. METHODS:In this study 15 healthy subjects (mean age 28.5?±?3.8 years) underwent 3?T MRN of the LSP area three times. The T2 values were calculated offline on a voxel-by-voxel basis and measured at three segments (preganglionic, ganglionic, postganglionic) of three LSP nerves (S1, L5, L4) by two independent investigators (experienced and novice). Normative data for the different nerves were extracted and intraclass correlation coefficients (ICCs) were calculated to assess reproducibility and interobserver reliability of T2 measurements. RESULTS:The T2 mapping showed excellent reproducibility with ICCs ranging between 0.99 (S1 preganglionic) and 0.89 (L5 postganglionic). Interobserver reliability was less robust with ICCs ranging between 0.78 (S1 preganglionic) and 0.44 (L5 postganglionic) for S1 and L5. A mean T2 value of 74.6?±?4.7?ms was registered for preganglionic segments, 84.7?±?4.1?ms for ganglionic and 65.4?±?2.5?ms for postganglionic segments, respectively. There was a statistically significant variation of T2 values across the nerve (preganglionic vs ganglionic vs postganglionic) for S1, L5, and L4. CONCLUSION:Our approach enables isotropic high-resolution and B1-insensitive T2 mapping of LSP nerves with excellent reproducibility. It might reflect a robust and clinically useful method for future diagnostics of LSP pathologies.

SUBMITTER: Sollmann N

PROVIDER: S-EPMC6579865 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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High Isotropic Resolution T2 Mapping of the Lumbosacral Plexus with T2-Prepared 3D Turbo Spin Echo.

Sollmann Nico N Weidlich Dominik D Cervantes Barbara B Klupp Elisabeth E Ganter Carl C Kooijman Hendrik H Rummeny Ernst J EJ Zimmer Claus C Kirschke Jan S JS Karampinos Dimitrios C DC

Clinical neuroradiology 20180110 2

<h4>Purpose</h4>Isotropic high-resolution three-dimensional (3D) magnetic resonance neurography (MRN) is increasingly used to depict even small and highly oblique nerves of the lumbosacral plexus (LSP). The present study introduces a T2 mapping sequence (T2-prepared 3D turbo spin echo) that is B1-insensitive and enables quantitative assessment of LSP nerves.<h4>Methods</h4>In this study 15 healthy subjects (mean age 28.5 ± 3.8 years) underwent 3 T MRN of the LSP area three times. The T2 values w ...[more]

PMID: 29322233

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Project description:Background/Aim: The turbo spin-echo (TSE) sequence is widely used for musculoskeletal (MSK) imaging; however, its acquisition speed is limited and can be easily affected by motion artifacts. We aimed to evaluate whether the use of a simultaneous multi-slice TSE (SMS-TSE) sequence can accelerate MSK imaging while maintaining image quality when compared with the routine TSE sequence. Methods: We prospectively enrolled 71 patients [mean age, 37.43 ± 12.56 (range, 20-67) years], including 37 men and 34 women, to undergo TSE and SMS sequences. The total scanning times for the wrist, ankle and knee joint with routine sequence were 14.92, 13.97, and 13.48 min, respectively. For the SMS-TSE sequence, they were 7.52, 7.20, and 6.87 min. Quantitative parameters, including the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR), were measured. Three experienced MSK imaging radiologists qualitatively evaluated the image quality of bone texture, cartilage, tendons, ligament, meniscus, and artifact using a 5-point evaluation system, and the diagnostic performance of the SMS-TSE sequences was evaluated. Results: Compared with the routine TSE sequences, the scanning time was lower by 49.60, 48.46, and 49.04% using SMS-TSE sequences for the wrist, ankle, and knee joints, respectively. For the SNR comparison, the SMS-TSE sequences were significantly higher than the routine TSE sequence for wrist (except for Axial-T2WI-FS), ankle, and knee joint MR imaging (all p < 0.05), but no statistical significance was obtained for the CNR measurement (all p > 0.05, except for Sag-PDWI-FS in ankle joint). For the wrist joint, the diagnostic sensitivity, specificity, and accuracy were 88.24, 100, and 92%. For the ankle joint, they were 100, 75, and 93.33%. For the knee joint, they were 87.50, 85.71, and 87.10%. Conclusion: The use of the SMS-TSE sequence in the wrist, ankle, and knee joints can significantly reduce the scanning time and show similar image quality when compared with the routine TSE sequence.

Project description:BackgroundThe black-blood (BB) technique was developed to suppress the signal from blood and cerebrospinal fluid (CSF) to provide improved depiction of vessel walls.PurposeThe aim was to compare three-dimensional turbo spin echo T1-weighted imaging (3D TSE T1WI) with or without two BB techniques (delay alternating with nutation for tailored excitation [DANTE], and improved motion-sensitized driven equilibrium [iMSDE]) for high-resolution magnetic resonance imaging (HR-MRI) of the vessel walls of intracranial arteries.Study typeProspective.PopulationFourteen healthy volunteers who underwent 3D T1WI for examination of intracranial vessel walls.Field strength/sequence3 Tesla, 3D TSE T1WI (SPACE and BrainVIEW) and BB (DANTE and iMSDE).AssessmentSPACE with or without DANTE, and BrainVIEW with or without iMSDE, were acquired in each subject. Two neuroradiologists independently assessed image quality, vessel wall delineation, BB effect, CSF, and acceptability using visual scoring systems, and measured signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in vessel walls, lumen, and CSF, while blinded to the presence and type of BB technique used.Statistical testsRepeated measures ANOVA or Friedman tests were performed for the comparisons, followed by Bonferroni correction.ResultsThe 3T T1WI sequences without BB are significantly superior in vessel wall delineation (P = 0.001). Black CSF scores were lower in SPACE with DANTE than SPACE without DANTE, and in BrainVIEW without iMSDE than SPACE without DANTE (P < 0.001). However, there were no significant differences in BB effect, image quality, and acceptability between the four 3D T1WI sequences (p > .05). The SNRVessel wall, CNRWall-Lumen, and CNRWall-CSF were higher (all p < .001) on SPACE with and without DANTE than on BrainVIEW with and without iMSDE. SNRLumen were higher (all p < .001) on BrainVIEW with and without iMSDE than on SPACE with and without DANTE. SNRCSF was higher (all p < .001) on BrainVIEW with iMSDE than on SPACE with DANTE.Data conclusionBoth 3D TSE T1WI sequences were acceptable for intracranial vessel wall evaluation, with or without BB techniques. Therefore, BB techniques may not necessarily be required with 3D TSE T1WI with a long ETL and TR (below 1160 ms).

Dataset Information

High Isotropic Resolution T2 Mapping of the Lumbosacral Plexus with T2-Prepared 3D Turbo Spin Echo.

Publications

High Isotropic Resolution T2 Mapping of the Lumbosacral Plexus with T2-Prepared 3D Turbo Spin Echo.

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