Ontology highlight
ABSTRACT:
SUBMITTER: Fulop GA
PROVIDER: S-EPMC6580383 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Fulop Gabor A GA Tarantini Stefano S Yabluchanskiy Andriy A Molnar Andrea A Prodan Calin I CI Kiss Tamas T Csipo Tamas T Lipecz Agnes A Balasubramanian Priya P Farkas Eszter E Toth Peter P Sorond Farzaneh F Csiszar Anna A Ungvari Zoltan Z
American journal of physiology. Heart and circulatory physiology 20190308 5
There has been an increasing appreciation of the role of vascular contributions to cognitive impairment and dementia (VCID) associated with old age. Strong preclinical and translational evidence links age-related dysfunction and structural alterations of the cerebral arteries, arterioles, and capillaries to the pathogenesis of many types of dementia in the elderly, including Alzheimer's disease. The low-pressure, low-velocity, and large-volume venous circulation of the brain also plays critical ...[more]