Ontology highlight
ABSTRACT:
SUBMITTER: Spektor R
PROVIDER: S-EPMC6581052 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Genome research 20190603 6
Chromatin features are characterized by genome-wide assays for nucleosome location, protein binding sites, three-dimensional interactions, and modifications to histones and DNA. For example, assay for transposase accessible chromatin sequencing (ATAC-seq) identifies nucleosome-depleted (open) chromatin, which harbors potentially active gene regulatory sequences; and bisulfite sequencing (BS-seq) quantifies DNA methylation. When two distinct chromatin features like these are assayed separately in ...[more]