Ontology highlight
ABSTRACT:
SUBMITTER: Jiang J
PROVIDER: S-EPMC6582147 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Jiang Jicai J Cole John B JB Freebern Ellen E Da Yang Y VanRaden Paul M PM Ma Li L
Communications biology 20190618
A hundred years of data collection in dairy cattle can facilitate powerful studies of complex traits. Cattle GWAS have identified many associated genomic regions. With increasing numbers of cattle sequenced, fine-mapping of causal variants is becoming possible. Here we imputed selected sequence variants to 27,214 Holstein bulls that have highly reliable phenotypes for 35 production, reproduction, and body conformation traits. We performed single-marker scans for the 35 traits and multi-trait tes ...[more]