Unknown

Dataset Information

0

Large-duct cholangiopathies: aetiology, diagnosis and treatment.


ABSTRACT: Cholangiopathies describe a group of conditions affecting the intrahepatic and extrahepatic biliary tree. Impairment to bile flow and chronic cholestasis cause biliary inflammation, which leads to more permanent damage such as destruction of the small bile ducts (ductopaenia) and biliary cirrhosis. Most cholangiopathies are progressive and cause end-stage liver disease unless the physical obstruction to biliary flow can be reversed. This review considers large-duct cholangiopathies, such as primary sclerosing cholangitis, ischaemic cholangiopathy, portal biliopathy, recurrent pyogenic cholangitis and Caroli disease.

SUBMITTER: Menon S 

PROVIDER: S-EPMC6583582 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature

altmetric image

Publications

Large-duct cholangiopathies: aetiology, diagnosis and treatment.

Menon Shyam S   Holt Andrew A  

Frontline gastroenterology 20190104 3


Cholangiopathies describe a group of conditions affecting the intrahepatic and extrahepatic biliary tree. Impairment to bile flow and chronic cholestasis cause biliary inflammation, which leads to more permanent damage such as destruction of the small bile ducts (ductopaenia) and biliary cirrhosis. Most cholangiopathies are progressive and cause end-stage liver disease unless the physical obstruction to biliary flow can be reversed. This review considers large-duct cholangiopathies, such as prim  ...[more]

Similar Datasets

| S-EPMC4533104 | biostudies-literature
| S-EPMC6915345 | biostudies-literature
| S-EPMC6161480 | biostudies-literature
| S-EPMC7106534 | biostudies-literature
| S-EPMC7154090 | biostudies-literature
| S-EPMC7115373 | biostudies-literature
| S-EPMC5597976 | biostudies-literature
| S-EPMC4501454 | biostudies-literature
| S-EPMC7234906 | biostudies-literature
| S-EPMC4128902 | biostudies-literature