Personalized nutrition: pretreatment glucose metabolism determines individual long-term weight loss responsiveness in individuals with obesity on low-carbohydrate versus low-fat diet.

ABSTRACT: BACKGROUND/OBJECTIVES:The interaction between fasting plasma glucose (FPG) and fasting insulin (FI) concentrations and diets with different carbohydrate content were studied as prognostic markers of weight loss as recent studies up to 6 months of duration have suggested the importance of these biomarkers. SUBJECTS/METHODS:This was a retrospective analysis of a clinical trial where participants with obesity were randomized to an ad libitum low-carbohydrate diet or a low-fat diet with low energy content (1200-1800?kcal/day [??5.0-7.5?MJ/d]; ??30% calories from fat) for 24 months. Participants were categorized (pretreatment) as normoglycemic (FPG?

SUBMITTER: Hjorth MF 

PROVIDER: S-EPMC6584064 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature