Unknown

Dataset Information

0

Multiplex optical detection and quantification of DNA fragments by metallo-peptide assemblies.


ABSTRACT: Rapid detection of infectious agents such as bacteria and viruses are important for proper health management, agriculture and homeland security. This paper presents a multiplex DNA detection system self-assembled by a metallo-peptide complex. Within five minutes, the system can simultaneously detect multiple DNA fragments, without any need for their separation. The presence of proteins in the sample does not harm the detection capabilities of the system, which can discriminate even between one base-pair mismatch and can perform at concentrations as low as 200 pM.

SUBMITTER: Saha A 

PROVIDER: S-EPMC6584589 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

altmetric image

Publications

Multiplex optical detection and quantification of DNA fragments by metallo-peptide assemblies.

Saha Abhijit A   Reches Meital M  

Scientific reports 20190619 1


Rapid detection of infectious agents such as bacteria and viruses are important for proper health management, agriculture and homeland security. This paper presents a multiplex DNA detection system self-assembled by a metallo-peptide complex. Within five minutes, the system can simultaneously detect multiple DNA fragments, without any need for their separation. The presence of proteins in the sample does not harm the detection capabilities of the system, which can discriminate even between one b  ...[more]

Similar Datasets

| S-EPMC4929498 | biostudies-literature
| S-EPMC1087790 | biostudies-literature
| S-EPMC3756973 | biostudies-literature
| S-EPMC3826651 | biostudies-literature
| S-EPMC4601099 | biostudies-literature
| S-EPMC1087789 | biostudies-literature
| S-EPMC3485162 | biostudies-literature
| S-EPMC5064307 | biostudies-literature
| S-EPMC7200677 | biostudies-literature
| S-EPMC8412074 | biostudies-literature