Ontology highlight
ABSTRACT:
SUBMITTER: Rubin SJS
PROVIDER: S-EPMC6584653 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Rubin Samuel J S SJS Bai Lawrence L Haileselassie Yeneneh Y Garay Gotzone G Yun Chohee C Becker Laren L Streett Sarah E SE Sinha Sidhartha R SR Habtezion Aida A
Nature communications 20190619 1
Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis. Each disease is characterized by a diverse set of potential manifestations, which determine patients' disease phenotype. Current understanding of phenotype determinants is limited, despite increasing prevalence and healthcare costs. Diagnosis and monitoring of disease requires invasive procedures, such as endoscopy and tissue biopsy. Here we report signatures of heterogeneity between disease diagnoses and phenotype ...[more]