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Graph-Theoretic Analysis of Belief System Dynamics under Logic Constraints.

ABSTRACT: Opinion formation cannot be modeled solely as an ideological deduction from a set of principles; rather, repeated social interactions and logic constraints among statements are consequential in the construct of belief systems. We address three basic questions in the analysis of social opinion dynamics: (i) Will a belief system converge? (ii) How long does it take to converge? (iii) Where does it converge? We provide graph-theoretic answers to these questions for a model of opinion dynamics of a belief system with logic constraints. Our results make plain the implicit dependence of the convergence properties of a belief system on the underlying social network and on the set of logic constraints that relate beliefs on different statements. Moreover, we provide an explicit analysis of a variety of commonly used large-scale network models.

SUBMITTER: Nedic A

PROVIDER: S-EPMC6586829 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Graph-Theoretic Analysis of Belief System Dynamics under Logic Constraints.

Nedić Angelia A Olshevsky Alex A Uribe César A CA

Scientific reports 20190620 1

Opinion formation cannot be modeled solely as an ideological deduction from a set of principles; rather, repeated social interactions and logic constraints among statements are consequential in the construct of belief systems. We address three basic questions in the analysis of social opinion dynamics: (i) Will a belief system converge? (ii) How long does it take to converge? (iii) Where does it converge? We provide graph-theoretic answers to these questions for a model of opinion dynamics of a ...[more]

PMID: 31221988

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Project description:BACKGROUND: Large-scale protein interaction maps provide a new, global perspective with which to analyse protein function. PSIMAP, the Protein Structural Interactome Map, is a database of all the structurally observed interactions between superfamilies of protein domains with known three-dimensional structure in the PDB. PSIMAP incorporates both functional and evolutionary information into a single network. RESULTS: We present a global analysis of PSIMAP using several distinct network measures relating to centrality, interactivity, fault-tolerance, and taxonomic diversity. We found the following results: Centrality: we show that the center and barycenter of PSIMAP do not coincide, and that the superfamilies forming the barycenter relate to very general functions, while those constituting the center relate to enzymatic activity. Interactivity: we identify the P-loop and immunoglobulin superfamilies as the most highly interactive. We successfully use connectivity and cluster index, which characterise the connectivity of a superfamily's neighbourhood, to discover superfamilies of complex I and II. This is particularly significant as the structure of complex I is not yet solved. Taxonomic diversity: we found that highly interactive superfamilies are in general taxonomically very diverse and are thus amongst the oldest. Fault-tolerance: we found that the network is very robust as for the majority of superfamilies removal from the network will not break up the network. CONCLUSIONS: Overall, we can single out the P-loop containing nucleotide triphosphate hydrolases superfamily as it is the most highly connected and has the highest taxonomic diversity. In addition, this superfamily has the highest interaction rank, is the barycenter of the network (it has the shortest average path to every other superfamily in the network), and is an articulation vertex, whose removal will disconnect the network. More generally, we conclude that the graph-theoretic and taxonomic analysis of PSIMAP is an important step towards the understanding of protein function and could be an important tool for tracing the evolution of life at the molecular level.

Dataset Information

Graph-Theoretic Analysis of Belief System Dynamics under Logic Constraints.

Publications

Graph-Theoretic Analysis of Belief System Dynamics under Logic Constraints.

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