Ontology highlight
ABSTRACT:
SUBMITTER: Sabir MS
PROVIDER: S-EPMC6588472 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Sabir Marya S MS Blauwendraat Cornelis C Ahmed Sarah S Serrano Geidy E GE Beach Thomas G TG Perkins Matthew M Rice Ann C AC Masliah Eliezer E Morris Christopher M CM Pihlstrom Lasse L Pantelyat Alexander A Resnick Susan M SM Cookson Mark R MR Hernandez Dena G DG Albert Marilyn M Dawson Ted M TM Rosenthal Liana S LS Houlden Henry H Pletnikova Olga O Troncoso Juan J Scholz Sonja W SW
Neurobiology of disease 20190221
Atypical parkinsonism syndromes are a heterogeneous group of neurodegenerative disorders that include corticobasal degeneration (CBD), Lewy body dementia (LBD), multiple system atrophy (MSA), and progressive supranuclear palsy (PSP). The APOE ε4 allele is a well-established risk factor for Alzheimer's disease; however, the role of APOE in atypical parkinsonism syndromes remains controversial. To examine the associations of APOE ε4 and ε2 alleles with risk of developing these syndromes, a total o ...[more]