Ontology highlight
ABSTRACT:
SUBMITTER: Mazzone M
PROVIDER: S-EPMC6589442 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Mazzone Massimiliano M Bergers Gabriele G
Annual review of physiology 20190201
Research over the last decades has provided strong evidence for the pivotal role of the tumor-associated blood and lymphatic vasculature in supporting immunoevasion and in subverting T cell-mediated immunosurveillance. Conversely, tumor blood and lymphatic vessel growth is in part regulated by the immune system, with infiltrating innate as well as adaptive immune cells providing both immunosuppressive and various angiogenic signals. Thus, tumor angiogenesis and escape of immunosurveillance are t ...[more]