Ontology highlight
ABSTRACT:
SUBMITTER: Taher S
PROVIDER: S-EPMC6589605 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Taher Shèdy S Borja Yamilette Y Cabanela Lucía L Costers Vincent J VJ Carson-Marino Morgan M Bailes Julie C JC Dhar Biswadeep B Beckworth Mark T MT Rabaglino Maria B MB Post Uiterweer Emiel D ED Conrad Kirk P KP
American journal of physiology. Regulatory, integrative and comparative physiology 20190320 5
We investigated expression of cholecystokinin (CCK) in humans and mice, and the bitter taste receptor TAS2R14 in the human placenta. Because CCK and gastrin activate the CCKBR receptor, we also explored placental gastrin expression. Finally, we investigated calcium signaling by CCK and TAS2R14. By RT-PCR, we found <i>CCK/Cck</i> and <i>GAST/Gast</i> mRNA expression in both normal human and mouse placentas, as well as in human trophoblast cell lines (TCL). Although both <i>Cckar</i> and -<i>br</i ...[more]