Ontology highlight
ABSTRACT:
SUBMITTER: Mitelman F
PROVIDER: S-EPMC6590459 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Mitelman Felix F Johansson Bertil B Mertens Fredrik F Schyman Tommy T Mandahl Nils N
Genes, chromosomes & cancer 20181226 3
Cancer cells are characterized by chromosome abnormalities, of which some, in particular balanced rearrangements, are associated with distinct tumor entities and/or with specific gene rearrangements that represent important steps in the carcinogenic process. However, the vast majority of cytogenetically detectable structural aberrations in cancer cells have not been characterized at the nucleotide level; hence, their importance and functional consequences are unknown. By ascertaining the chromos ...[more]